Red palm oil extract | 20% palm phytonutrients
Contains dozens of naturally occurring fat-soluble tocotrienols, tocopherols, and carotenoids. (1, 2) Toco-9 provides 160 mg of tocochromanols and 30 mg of carotenoids, which is supported by 35+ human clinical trials for their safety and effectiveness. (3–38).

 

Sesame seed extract | 90% sesamin
Contains a fat-soluble lignan known as sesamin, which increases the body's retention of the vitamin E family, including tocotrienols and tocopherols. (39, 40) Each serving provides 90 mg of sesamin which is clinically effective for enhancing the benefits from palm-based phytonutrients. (41–43).

 

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Hypromellose capsule | water‑sealed
Made from 100% plant-based cellulose material. The capsule is hermetically sealed to help protect the oxygen sensitive ingredients. Our liquid encapsulation technology avoids all chemical preservatives, fillers, and binders.

 

Supports the skin’s UV defense

Supports the skin's natural defense against UVA and UVB to minimize redness and photoaging from mild sun exposure. (1–3)

 

Shown to increase the skin's tolerance to sunlight by up to 240% after 12 weeks of supplementation in healthy adults. (1-4)

Carotenoids, tocochromanols, and sesamin help dissipate UV radiation from the sun by supporting the skin’s natural antioxidant functions. (8-10) This helps protect the skin’s DNA, cellular membranes, and collagen from mild sun exposure. (1, 4–7)

It is recommended to supplement with Toco-9 daily for at least 12 weeks for the greatest sun protective benefits. (9) Toco-9 is not intended to replace sunscreen or other effective sun protective measures.

 

Regenerates youthful skin

Enhances skin softness and hydration, and prevents age-related DNA damage. (1–4, ‡)

 

Shown to significantly reduce the appearance of wrinkles after 4 weeks in healthy middle-aged women. (1, ‡)

Improves skin health by restoring cellular hydration, stimulating synthesis of type-1 collagen, and reducing DNA damage associated with aging. (2–6)

For the best results, it is recommended to supplement with Toco-9 daily for at least 12 weeks to achieve full saturation of tocochromanols and carotenoids throughout the dermis and epidermis. (7–9)

 

Reverses age-related hair loss

Increases the number of hairs on the scalp, without side-effects. (1, 2)

 

Shown to increase the number of hairs on the scalp by an average of 38% after 8 months in men and women suffering from age-related hair loss. (1, 2)

Triggers hair growth by stimulating insulin like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF), and keratinocyte growth factor (KGF) in aging hair follicles. (3–6)

Toco-9 can be used safely with minoxidil (Rogaine®) and/or finasteride (Propecia®). It is recommended by cosmetic surgeons to supplement with the palm-based extract in Toco-9 before and after hair transplantation surgery for the most successful hair regrowth. (7)

References

• Ingredients
• Protects skin from UV damage
• Regenerates youthful skin
• Reverses age related hair loss

• References

  Toco-9 Ingredients

  Iconic Formulations ensures all ingredients meet FDA GMP requirements and are verified to be free of harmful pesticides, solvents, heavy metals, aflatoxins, and other contaminates.

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  5. Césarini JP, Michel L, Maurette JM, et al. 2003. Immediate effects of UV radiation on the skin: modification by an antioxidant complex containing carotenoids. Photodermatol. Photoimmunol. Photomed. 19(4):182–89
  6. Heinrich U, Gärtner C, Wiebusch M, et al. 2003. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. J. Nutr. 133(1):98–101
  7. Yamashita E. 2002. Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on skin. FOOD Style. 21(6(6)):112–17
  8. Stahl W, Heinrich U, Jungmann H, et al. 2000. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light–induced erythema in humans.Am. J. Clin. Nutr. 71(3):795–98
  9. Lee J, Jiang S, Levine N, et al. 2000. Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure. Proc. Soc. Exp. Biol. Med. 223(2):170–74
  10. Gollnick HPM, Hopfenmüller W, Hemmes C, et al. 1996. Systemic beta carotene plus topical UV-sunscreen are an optimal protection against harmful effects of natural UV-sunlight: results of the berlin-eilath study. European journal of dermatology. 6(3)(200-205)
  11. Beoy LA, Woei WJ, Hay* YK. 2010. Effects of tocotrienol supplementation on hair growth in humans. Tropical Life Sciences Research. 21(2):91–99
  12. Ho DSS, Yuen KH, Wong JW, et al. 2007. Palm fruit extract for hair growth: a human clinical trial. US Patent 7211274 B2
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  17. Magosso E. 2010. Tocotrienols and nonalcoholic fatty liver: a clinical experience
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  21. Torbergsen AC, Collins AR. 2000. Recovery of human lymphocytes from oxidative DNA damage; the apparent enhancement of dna repair by carotenoids is probably simply an antioxidant effect. Eur. J. Nutr. 39(2):80–85
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  39. Frank J, Lee S, Leonard SW, et al. 2008. Sex diffs in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects. Am. J. Clin. Nutr. 87(6):1723–29
  40. Cooney RV, Custer LJ, Okinaka L, et al. 2001. Effects of dietary sesame seeds on plasma tocopherol levels. Nutr. Cancer. 39(1):66–71
  41. Yamada Y, Obayashi M, Ishikawa T, et al. 2008. Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. J. Nutr. Sci. Vitaminol. 54(2):117–23
  42. Takemoto D, Yasutake Y, Tomimori N, et al. 2015. Sesame lignans and vitamin E supplementation improve subjective statuses and anti-oxidative capacity in healthy humans with feelings of daily fatigue. Glob. J. Health Sci. 7(6):1–10
  43. Yamashita K, Iizuka Y, Imai T, et al. 1995. Sesame seed and its lignans produce marked enhancement of vitamin e activity in rats fed a low alpha-tocopherol diet. Lipids. 30(11):1019–28
• Protects skin from UV damage Césarini JP, Michel L, Maurette JM, et al. 2003. Immediate effects of UV radiation on the skin: modification by an antioxidant complex containing carotenoids. Photodermatol. Photoimmunol. Photomed. 19(4):182–89 Lee J, Jiang S, Levine N, et al. 2000. Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure. Proc. Soc. Exp. Biol. Med. 223(2):170–74 Gollnick HPM, Hopfenmüller W, Hemmes C, et al. 1996. Systemic beta-carotene plus topical UV-sunscreen are an optimal protection against harmful effects of natural UV-sunlight: results of the berlin-eilath study. European journal of dermatology. 6(3)(200-205) Stahl W, Heinrich U, Jungmann H, et al. 2000. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light–induced erythema in humans. Am. J. Clin. Nutr. 71(3):795–98 Yamada Y, Obayashi M, Ishikawa T, et al. 2008. Dietary tocotrienol reduces uvb-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. J. Nutr. Sci. Vitaminol. 54(2):117–23 Shibata A, Nakagawa K, Kawakami Y, et al. 2010. Suppression of gamma-tocotrienol on UVB induced inflammation in hacat keratinocytes and hr-1 hairless mice via inflammatory mediators multiple signaling. J. Agric. Food Chem. 58(11):7013–20 Traber MG, Podda M, Weber C, et al. 1997. Diet-derived and topically applied tocotrienols accumulate in skin and protect the tissue against ultraviolet light-induced oxidative stress. Asia Pac. J. Clin. Nutr. 6(1):63–67 Meinke MC, Friedrich A, Tscherch K, et al. 2012. Influence of dietary carotenoids on radical scavenging capacity of the skin and skin lipids. Eur. J. Pharm. Biopharm. 84(2):365–73 Stahl W, Sies H. 2012. β-carotene and other carotenoids in protection from sunlight. Am. J. Clin. Nutr. 96(5):1179S – 84S Chen L, Hu JY, Wang SQ. 2012. The role of antioxidants in photoprotection: a critical review. J. Am. Acad. Dermatol. 67(5):1013–24
• References Regenerates youthful skin ‡ The claims related to improved skin appearance are substantiated with a study that used 40 mg tocotrienols and 2 mg astaxanthin per day. Palm Fruit™ contains at least 52 mg tocotrienols per serving, and although Palm Fruit™ does not contain astaxanthin, it contains 30 mg of carotenoids with similar structure and function as astaxanthin, and thus may provide comparable effects. Yamashita E. 2002. Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on skin. FOOD Style. 21(6(6)):112–17 Chin S-F, Hamid NAA, Latiff AA, et al. 2007. Reduction of DNA damage in older healthy adults by Tri E tocotrienol supplementation. Nutrition. 24(1):1–10 Astley SB, Elliott RM, Archer DB, et al. 2004. Evidence that dietary supplementation with carotenoids and carotenoid-rich foods modulates the DNA damage: repair balance in human lymphocytes. Br. J. Nutr. 91(1):63–72 Torbergsen AC, Collins AR. 2000. Recovery of human lymphocytes from oxidative DNA damage; the apparent enhancement of dna repair by carotenoids is probably simply an antioxidant effect. Eur. J. Nutr. 39(2):80–85 Makpol S, Azura Jam F, Anum Mohd Yusof Y, et al. 2011. Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction. Arch. Med. Sci. 7(5):889–95 Makpol S, Jam FA, Khor SC, et al. 2013. Comparative effects of biodynes, tocotrienol-rich fraction, and tocopherol in enhancing collagen synthesis and inhibiting collagen degradation in stress-induced premature senescence model of human diploid fibroblasts. Oxid. Med. Cell. Longev. 2013:298574 Patel V, Rink C, Gordillo GM, et al. 2012. Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients. J. Nutr. 142(3):513–19 Stahl W, Heinrich U, Jungmann H, et al. 1998. Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting betatene. J. Nutr. 128(5):903–7 Blume-Peytavi U, Rolland A, Darvin ME, et al. 2009. Cutaneous lycopene and beta-carotene levels measured by resonance raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation. Eur. J. Pharm. Biopharm. 73(1):187–94
• References Reverses age related hair loss Ho DSS, Yuen KH, Wong JW, et al. 2007. Palm fruit extract for hair growth: a human clinical trial. US Patent 7211274 B2 Beoy LA, Woei WJ, Hay YK. 2010. Effects of tocotrienol supplementation on hair growth in humans. Tropical Life Sciences Research. 21(2):91–99 Choi J-S, Jeon M-H, Moon W-S, et al. 2014. In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid. Biol. Pharm. Bull. 37(1):44–53 Panchaprateep R, Asawanonda P. 2014. Insulin-like growth factor-1: roles in androgenetic alopecia. Exp. Dermatol. Li W, Man X-Y, Li C-M, et al. 2012. VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK. Exp. Cell Res. 318(14):1633–40 Jang J-H. 2005. Stimulation of human hair growth by the recombinant human keratinocyte growth factor-2 (KGF-2). Biotechnol. Lett. 27(11):749–52 Rinaldi F, Bezzola P, Sorbellini E. 2003. The “substrate to energy” the importance of the diet and nutritional supplements in metabolic process of the hair bulb before and after transplant. EUROPEAN SOCIETY OF HAIR RESTORATION SURGERY. 3(2)